The University Medical Center Göttingen (UMG) unites the Medical Faculty of Georg-August University and the University Hospital in an integration model. With over 9,700 employees, the UMG and its subsidiaries are one of the largest employers in the region. More than 60 clinics, institutes and departments stand for high-quality patient care, excellent research and modern teaching.

Göttingen as a city of science is located in the center of Germany and the University Medical Center Göttingen is integrated into an attractive network of university and non-university scientific institutions.

Our goal as University Medical Center Göttingen is professional equality for all genders. We strive to equalize the gender ratio in areas where there is underrepresentation. The University Medical Center Göttingen is particularly committed to the professional participation of severely disabled people and therefore welcomes applications from severely disabled people. In the case of equal suitability, applications from severely disabled persons will be given preferential consideration in accordance with the relevant regulations. We kindly ask you to indicate a disability/equal status in your letter of application in order to safeguard your interests.

The Klinik für Allgemein-, Viszeral- und Kinderchirurgie of the University Medical Centre Göttingen is looking for a new position for the earliest start date

Postdoctoral Scientist Position (f/m/d)

full time, hours per week, limited to 2 yearsRemuneration according to TV-L E13

Therapy Development for Gastrointestinal Cancers
We are deploying cellular human and murine model systems including patient-derived organoids to study molecular and translational aspects of therapies relevant for GI cancers (e.g. Advanced Science, 2024, e2307695; Cell Mol Life Sci, 2022, 80: 12; Nature Methods, 2022, 19:803; JCI Insight, 2022, 7: e151353; EMBO Mol Med, 2022, 14:e14876; Cancer Res, 2022, 82:695; Nature Cancer, 2022, 3:318; Cancer Discov, 2021, 11:3158; Gut, 2020, 69:1472; https://chirurgie.umg.eu/forschung/ag-schneider-en/). We utilize these systems to uncover adaptive processes leading to therapy resistance. Consequently, the advertised projects focus on (1) identifying common processes established in drug-tolerant persister cells induced by both targeted and non-targeted therapies, and (2) exploiting this knowledge to develop novel therapeutic interventions.

Your tasks

Your tasks

• The successful candidate will have the opportunity to gain important insights into clinically relevant aspects of therapy resistance and will perform state-of-the-art experiments including barcoding approaches, NGS technologies, and drug/genetic screening experiments
• This includes learning and applying a wide spectrum of genetic, molecular & cell biology, and biochemical techniques to study aspects of cancer with a high translational potential

Your qualifications

Your qualifications

• You are a self-motivated and independent scientist (f/m/d) with a Ph.D. degree in biomedicine, biochemistry, biology, systems biology, or related fields with a specific interest in translational gastrointestinal cancer research
• Previous exposure to and experiences in basic and advanced cellular and molecular biology techniques are mandatory
• Strong knowledge in bioinformatics and data analysis, along with a keen interest in the molecular aspects of therapies, are essential
• The Postdoc is expected to be highly collaborative and pass on skills and knowledge to other team members and visitors
• You will be involved in the supervision of Ph.D. students and undergraduates
• Excellent communication skills for scientific discussion are indispensable

We offer

We offer

• Interesting, versatile workplace, with creative freedom in a highly collegial team
• Excellent framework conditions and state-of-the-art equipment
• Opportunity for international networking at the highest level

Our goal as University Medical Center Göttingen is professional equality for all genders. We strive to equalize the gender ratio in areas where there is underrepresentation. The University Medical Center Göttingen is particularly committed to the professional participation of severely disabled people and therefore welcomes applications from severely disabled people. In the case of equal suitability, applications from severely disabled persons will be given preferential consideration in accordance with the relevant regulations. We kindly ask you to indicate a disability/equal status in your letter of application in order to safeguard your interests.

We look forward to receiving your application!

Universitätsmedizin Göttingen
Klinik für Allgemein-, Viszeral- und Kinderchirurgie
Professor Doctor Günter Schneider

Robert-Koch-Straße 40
37075 Göttingen
0551/39-20488
https://chirurgie.umg.eu/

Universitätsmedizin Göttingen
Georg-August-Universität
Robert-Koch-Straße 40
37075 Göttingen